The first and only CDK4 & 6 inhibitor that can be taken every day for women newly diagnosed with HR+, HER2– metastatic breast cancer.
150 mg or 200 mg orally twice a day, as directed by your doctor.
CDK4 & 6=cyclin-dependent kinases 4 and 6; HER2–=human epidermal growth factor receptor 2–negative; HR+=hormone receptor positive; MBC=metastatic breast cancer.
Important Facts About Verzenio® (ver-ZEN-ee-oh). It is also known as abemaciclib.
Verzenio is a prescription medicine used to treat a type of breast cancer. It is a medicine you can take if:
It is not known if Verzenio is safe and effective in children.
Warnings
Verzenio may cause serious side effects, including:
Diarrhea is common with Verzenio, may be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. Your doctor may stop your treatment, lower your dose, or tell you to wait to begin your treatment cycle if you have diarrhea.
At the first sign of loose stools, tell your doctor. You may be advised to start taking an antidiarrheal medicine (such as loperamide) and drink more fluids.
Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your doctor should check your white blood cell counts before and during treatment. Tell your doctor right away if you have fever or chills.
Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. Tell your healthcare provider right away if you have any new or worsening symptoms, including:
Verzenio can cause liver problems. Tell your doctor right away if you have any of the following signs or symptoms of liver problems:
Verzenio may cause blood clots in your veins or lungs. These may be serious and have led to death. Tell your doctor if you have the following signs and symptoms of a blood clot:
Verzenio can harm your unborn baby. Use effective birth control during treatment and for at least 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.
Common side effects
The most common side effects of Verzenio include:
These are not all the possible side effects of Verzenio.
Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.
Before using
Before you use Verzenio, tell your doctor:
How to take
Learn more
For more information, call 1-800-545-5979.
This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Verzenio and how to take it. Your doctor is the best person to help you decide if Verzenio is right for you.
Verzenio® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.
AL CON BS 20SEP2019