About Verzenio
Whether you're newly diagnosed or just starting treatment, learn more about Verzenio and hear the experiences of other real relentless women.
What is Verzenio?
Verzenio is a targeted treatment known as a CDK4 & 6 inhibitor. Verzenio is a non-chemotherapy oral tablet.
Verzenio is a targeted treatment, known as a CDK4 & 6 inhibitor, used to treat a type of breast cancer. It is a medicine you can take if you have a type of breast cancer called HR+, HER2– (hormone receptor positive/human epidermal growth factor receptor 2 negative) and the cancer has spread to other parts of the body (metastasized).
Verzenio is given with an aromatase inhibitor as initial endocrine-based therapy if you are postmenopausal, or male. If you are a female or male, and the cancer has gotten worse after hormone therapy, then Verzenio is given with fulvestrant. If you are female or male and the cancer has gotten worse after both hormone therapy and chemotherapy, then Verzenio is given by itself.
It is not known if Verzenio is safe and effective in children.
CDK4 & 6=cyclin-dependent kinases 4 and 6.
How Verzenio works
Verzenio works inside the cell to block CDK4 & 6 activity and help stop the growth of cancer cells, so they may eventually die*
Verzenio is a CDK4 & 6 inhibitor used to treat HR+, HER2– metastatic breast cancer. Verzenio works to block specific proteins called CDK4 & CDK6. CDK4 & 6 proteins help control how fast cells grow. These proteins, along with hormones like estrogen, play an important role in the growth and division process of normal cells.
But if you have HR+, HER2– breast cancer, CDK4 & 6 proteins become overactive, causing the cancer cells to grow and divide uncontrollably, which makes the tumor grow. This can also lead to cancer cells spreading to other parts of the body, which is called metastasis.
Verzenio can be taken alone, but it is usually taken with hormone therapy to slow the growth of cancer cells. Hormone therapy (aromatase inhibitor or fulvestrant) works outside the cell to help cut off estrogen that feeds the cancer. Verzenio works inside the cell to block CDK4 & 6 activity and help stop the growth of cancer cells, so they may eventually die.* When Verzenio inhibits CDK4 & 6 in healthy cells, it can lead to side effects, some of which may be serious.
*Based on pre-clinical studies.
How is Verzenio different?
Verzenio is taken differently—it's the first and only CDK4 & 6 inhibitor that can be taken every day, twice a day†
Verzenio is a CDK4 & 6 inhibitor. It is the first and only oral tablet of its kind that can be taken every day for the treatment of HR+, HER2– metastatic breast cancer.
Because Verzenio is an oral medication and not an infusion, you can take it in the convenience of your home. This may allow for more flexibility in your daily life. However, you may need to see your doctor for other treatments.
†150 mg or 200 mg orally twice a day, as directed by your doctor.
Explore an advancement in the treatment data for HR+, HER2– metastatic breast cancer
SELECT SAFETY INFORMATION
Verzenio may cause serious side effects, including:
Diarrhea is common with Verzenio, may be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. Your doctor may stop your treatment, lower your dose, or tell you to wait to begin your treatment cycle if you have diarrhea.
At the first sign of loose stools, tell your doctor. You may be advised to start taking an antidiarrheal medicine (such as loperamide) and drink more fluids.
See the story behind Verzenio, a treatment option for HR+, HER2– metastatic breast cancer
Every Day Matters
For women living with HR+, HER2– metastatic breast cancer, every day matters. Learn about an everyday, twice a day CDK4 & 6 inhibitor for a relentless disease.
Verzenio is taken every day, twice a day.
150 mg or 200 mg orally twice a day, as directed by your doctor.
SELECT SAFETY INFORMATION
Verzenio may cause serious side effects, including:
Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your doctor should check your white blood cell counts before and during treatment. Tell your doctor right away if you have fever or chills.
Real Relentless Women
Hear from real, relentless women living with metastatic breast cancer. For some, this includes Verzenio and how the treatment has impacted their story.
Jeanelle
Jeanelle is a real Verzenio patient who puts family first. In addition to spending time with her loved ones, Jeanelle finds an outlet through dance. She discusses how her diagnosis of metastatic breast cancer impacted her life and her time on treatment with Verzenio.
Nancy
For Nancy, a real Verzenio patient, being there for her family is everything to her. She talks about her feelings about her diagnosis as well as how treatment with Verzenio has helped her feel more hopeful.
Holly
Holly, a real Verzenio patient, restores a boat with her husband so they can spend their retirement sailing the world. They discuss how metastatic breast cancer and discovering Verzenio has impacted their lives.
Honey
Honey, a grandmother and real Verzenio patient, talks to her lifelong friend about everything they’ve been through, including her diagnosis with metastatic breast cancer.
Teresa
Teresa, a wife, mother, grandmother, and a real Verzenio patient, talks about her experience living with metastatic breast cancer, and her daughter talks about how it has impacted their entire family.
Karen
Karen, a patient advocate living with metastatic breast cancer, talks about empowering women like her around the world. Her sister tells Karen what an inspiration her strength is to her and so many other women.