How effective is Verzenio by itself?
Verzenio was studied in 132 adult patients with hormone receptor‑positive (HR+), human epidermal growth factor receptor 2 negative (HER2–) advanced or metastatic breast cancer (MBC) who had progressed on or after prior hormone treatments, a taxane, and 1 or 2 chemotherapy regimens in the metastatic setting. All patients were treated with only Verzenio.
Verzenio shrinks tumors and delays the spread of cancer
When other advanced or metastatic breast cancer treatments (hormonal treatments and prior chemotherapy) stopped working, Verzenio helped delay the growth and spread of cancer in a clinical study.
19.7% of women taking Verzenio alone saw their tumors shrink by 30% or more. In the same study, an independent review found similar results (17.4% of women).
SELECT SAFETY INFORMATION
Verzenio may cause serious side effects, including:
Diarrhea is common with Verzenio, may be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. Your doctor may stop your treatment, lower your dose, or tell you to wait to begin your treatment cycle if you have diarrhea.
At the first sign of loose stools, tell your doctor. You may be advised to start taking an antidiarrheal medicine (such as loperamide) and drink more fluids.
Taking Verzenio by itself
The recommended dose for Verzenio by itself is 200 mg twice daily, taken once in the morning and once at night.
You will receive 4 individual packs, each one containing your dose of 200-mg tablets for 7 days.
- Multiple tablet strengths (50 mg, 100 mg, 150 mg, and 200 mg) allow your doctor to make dose adjustments based on your tolerability
- If you need to reduce your dose due to tolerability, Verzenio is approved to be dosed as low as 50 mg twice daily, as directed by your doctor
- No matter what dose you are prescribed, you will take 1 tablet, 2 times a day, unless your doctor tells you otherwise