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African American woman standing strong

If You're Living with HR+/HER2– Metastatic Breast Cancer, More Time Is Possible

Verzenio was studied in a clinical trial of 669 women with HR+, HER2– metastatic breast cancer who progressed following prior hormone treatments. 446 patients were treated with Verzenio plus fulvestrant and 223 were treated with fulvestrant alone. In a clinical study 48.1% of women taking Verzenio + Fulvestrant saw their tumors shrink vs. 21.3% taking fulvestrant alone.

In a clinical study women taking Verzenio + fulvestrant lived for a median of 46.7 months vs 37.3 months on fulvestrant alone. In the same study, Verzenio + fulvestrant delayed disease progression for a median of 16.4 months vs 9.3 months with fulvestrant alone.

Undergoing treatment for metastatic breast cancer is one of the most difficult experiences a woman can take on. But you don't have to do it alone. With the links below, explore the information and resources designed to help support you and aid in your treatment.

Verzenio is the first and only treatment of its kind that can be taken everyday for the treatment of certain types of HR+, HER2– metastatic breast cancer - an everyday, twice daily treatment for a relentless disease.

Ask Your Doctor About Verzenio

00:01

[Live action opens on a Black woman in her forties positioned center frame, staring directly into camera.]

Narrator: When I received my metastatic breast cancer diagnosis,

00:07

[Live action cut to a close-up of an older couple’s hands.]

Narrator: I didn't need anyone to tell me that I was strong.

00:10

[Live action cut to a close-up of the older couple as they smile at each other.]

Narrator: What I needed was more time.

00:15

[As the husband leans into his wife, the Narrator begins. We cut to a close-up of the medication on the bathroom counter. We cut to the older woman as she places the pill in her mouth. We cut to a close-up of family pictures, the Verzenio logo fades out as we fade in the legal super.]

ANNCR Narrator: Verzenio + fulvestrant is proven to help women live significantly longer and is for HR+, HER2- metastatic breast cancer that has progressed after hormone therapy.

Caption: In a clinical study women taking Verzenio + fulvestrant lived for a median of 46.7 months vs 37.3 months on fulvestrant alone.

Logo: Verzenio® abemaciclib 50 | 100 | 150 | 200 mg tablets

00:20

[Close-up of family pictures continues. We cut back to the older woman as she grabs a glass of water.]

ANNCR Narrator: Diarrhea is common, may be severe, or cause dehydration or infection. At the first sign, call your doctor, start an antidiarrheal, and drink fluids.

Caption: At first sign of diarrhea, call your doctor, start an anti-diarrheal medication, and drink fluids.

00:28

[As she sips from her glass, we fade in the next legal super. We cut to a backyard where the family is having a cookout. We cut to another shot of the family at the cookout. We cut to a close-up of the younger woman as she ties on her headwrap.We cut to a wide shot of the younger woman smiling at the camera as we fade out the legal super.]

ANNCR Narrator: Before taking Verzenio, tell your doctor about any fever, chills, or other signs of infection. Verzenio may cause other potential side effects like low white blood cell counts, which may cause serious infection that can lead to death. Life-threatening lung inflammation can occur. Tell your doctor about any new or worsening trouble breathing, cough, or chest pain. Serious liver problems can happen. Symptoms include fatigue, appetite loss, stomach pain, and bleeding or bruising.

Caption: Common side effects include nausea, infections, low blood cells and platelets, decreased appetite, headache, abdominal pain, tiredness (fatigue), vomiting, and hair thinning or loss.

00:44

[We cut to the woman cooking in the kitchen with her son, legal super fades in. We cut to a shot of the son hugging his mother. We fade out the legal super.]

ANNCR Narrator: Blood clots that can lead to death have occurred. Tell your doctor if you have pain or swelling in your arms or legs, shortness of breath, chest pain and rapid breathing or heart rate, or if you are nursing, pregnant, or plan to be.

Caption: Tell your doctor about all your medical conditions and medications you take and if you are nursing, pregnant, or plan to be pregnant.

00:50

[We cut to a close-up profile of the older woman staring into the camera.]

Narrator: Strength is one thing.

00:51

[We cut to the older couple staring into the camera. We cut to the family in the front yard.]

Narrator: The chance to have more time with the people I love? That’s everything.

00:55

[Main End Card Screen with Lilly logo and Verzenio logo at the bottom]

Narrator: Ask your doctor about every day Verzenio.

Caption: More time is possible

Sub Caption: Verzenio.com/your-voice

Available by prescription only

For pricing information, please visit lillypricinginfo.com/verzenio or call 1-844-VERZENIO (1-844-837-9364)

Logo: Verzenio® abemaciclib 50 | 100 | 150 | 200 mg tablets

Logo: Lilly

00:57

[Frame 2 End Card with Lilly logo and Verzenio logo at the bottom and large Verzenio logo center screen]

Narrator: everyday Verzenio

Caption: Verzenio® abemaciclib 50 | 100 | 150 | 200 mg tablets

Verzenio.com/your-voice

Available by prescription only

For pricing information, please visit lillypricinginfo.com/verzenio or call 1-844-VERZENIO (1-844-837-9364)

Logo: Verzenio® abemaciclib 50 | 100 | 150 | 200 mg tablets

Logo: Lilly

Your Best Advocate


You don't need us to tell you that you are worthy of respect, empathy and understanding from your care team. If you feel like you're not being heard or understood during your medical appointments, it's your right to ask direct questions related to your concerns. Remember — it's your body and your care. You deserve answers.

Partnering With Your Doctor

Have the Talk


Despite being diagnosed at a similar rate to White women, Black women are 41% more likely to die from metastatic breast cancer than White women, and are often diagnosed at more advanced stages*.

That's why its so important to talk to the women in your life to connect with and support you.


More Connections

More Resources


We know how challenging it can be to navigate the medical care system during this critical time, so we've compiled additional information to help support you and aid in your care. Visit hhs.gov for information on patients rights and responsibilities under the Affordable Care Act.

See how you can save on treatment and get support along the way with the Verzenio Continuous Care Program.


More about Verzenio Continuous Care

* Source: Patterns and Trends in Age-Specific Black-White Differences in Breast Cancer Incidence and Mortality - United States, 1999-2014, CDC 2014

SAFETY SUMMARY

Warnings - Verzenio may cause serious side effects, including:

Diarrhea is common with Verzenio, may sometimes be severe and may cause dehydration or infection. The most common time to develop diarrhea is during the first month of Verzenio treatment. If you develop diarrhea during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, stop your treatment, or decrease your dose.

If you have any loose stools, start taking an antidiarrheal medicine (such as loperamide), drink more fluids, and tell your healthcare provider right away.

Low white blood cell counts (neutropenia) are common with Verzenio and may cause serious infections that can lead to death. Your healthcare provider should check your white blood cell counts before and during treatment. If you develop low white blood cell counts during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or wait before starting your next month of treatment. Tell your healthcare provider right away if you have signs and symptoms of low white blood cell counts or infections, such as fever and chills.

Verzenio may cause severe or life-threatening inflammation (swelling) of the lungs during treatment that can lead to death. If you develop lung problems during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it, decrease your dose, or stop your treatment. Tell your healthcare provider right away if you have any new or worsening symptoms, including:

  • Trouble breathing or shortness of breath
  • Cough with or without mucus
  • Chest pain

Verzenio can cause serious liver problems. Your healthcare provider should do blood tests to check your liver before and during treatment. If you develop liver problems during treatment with Verzenio, your health care provider may reduce your dose or stop your treatment. Tell your healthcare provider right away if you have any of the following signs or symptoms of liver problems:

  • Feeling very tired
  • Pain on the upper right side of your stomach area (abdomen)
  • Loss of appetite
  • Bleeding or bruising more easily than normal

Verzenio may cause blood clots in your veins, or in the arteries of your lungs. Verzenio may cause serious blood clots that have led to death. If you develop blood clots during treatment with Verzenio, your healthcare provider may tell you to temporarily stop taking it. Tell your healthcare provider right away if you have any of the following signs and symptoms of a blood clot:

  • Pain or swelling in your arms or legs
  • Shortness of breath
  • Chest pain
  • Fast breathing
  • Fast heart rate

Verzenio can harm your unborn baby. Use effective birth control (contraception) during treatment and for 3 weeks after the last dose of Verzenio and do not breastfeed during treatment with Verzenio and for at least 3 weeks after your last dose. Verzenio may affect the ability of males to father a child.

Common side effects

The most common side effects of Verzenio include:

  • Nausea
  • Infections
  • Low red blood cell counts (anemia)
  • Decreased appetite
  • Headache
  • Hair thinning or hair loss (alopecia)
  • Abdominal pain
  • Tiredness
  • Low white blood cell counts (leukopenia)
  • Vomiting
  • Low platelet counts (thrombocytopenia)

These are not all the possible side effects of Verzenio

Tell your healthcare provider if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using:

Before you use Verzenio, tell your healthcare provider about all your medical conditions, including:

  • If you have fever, chills, or other signs of infection.
  • If you have a history of blood clots in your veins.
  • Have lung or breathing problems.
  • Have liver or kidney problems.
  • If you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that contains ketoconazole.

How to take:

  • Take Verzenio exactly as your healthcare provider tells you.
  • Your healthcare provider may change your dose if needed. Do not stop taking Verzenio or change the dose without talking to your healthcare provider.
  • Verzenio may be taken with or without food.
  • Swallow Verzenio tablets whole. Do not chew, crush, or split the tablets before swallowing. Do not take Verzenio tablets if they are broken, cracked, or damaged.
  • Take your doses of Verzenio at about the same time every day.
  • If you vomit or miss a dose of Verzenio, take your next dose at your regular time. Do not take 2 doses at the same time to make up for the missed dose.

What to avoid during treatment

  • Avoid taking ketoconazole during treatment with Verzenio. Tell your healthcare provider if you take a medicine that contains ketoconazole
  • Avoid grapefruit and products that contain grapefruit during treatment with Verzenio. Grapefruit may increase the amount of Verzenio in your blood

Learn more

Verzenio is a prescription medicine. For more information, call 1-800-545-5979.

This summary provides basic information about Verzenio but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Verzenio and how to take it. Your healthcare provider is the best person to help you decide if Verzenio is right for you.

AL CON BS 14SEP2022

Verzenio® is a registered trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

INDICATIONS

Verzenio® (ver-ZEN-ee-oh) is used to treat certain types of breast cancer known as HR+/HER2– (hormone receptor positive/human epidermal growth factor receptor 2 negative) breast cancer.

It is a medicine you can take if:

  • You have node-positive early breast cancer that has a high risk of coming back as determined by your healthcare provider. Verzenio is given along with hormonal therapy to women and men.
  • Or, the cancer has spread to other parts of the body (metastasized). If you are postmenopausal, or male, then Verzenio is given with an aromatase inhibitor as initial endocrine-based therapy. If you are a female or male, and the cancer has gotten worse after hormonal therapy, then Verzenio is given with fulvestrant. If you are female or male and the cancer has gotten worse after both hormonal therapy and chemotherapy, then Verzenio is given by itself.

It is not known if Verzenio is safe and effective in children.

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Verzenio® is a registered trademark and Verzenio Continuous Care™ is a trademark owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

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Other product/company names mentioned herein are the trademarks of their respective owners.

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